L Carnitine. Boost Weight Loss & Improve Heart Health Early research into L carnitine was often cited as underwhelming, showing negligible changes in muscle carnitine content and fat loss outcomes. However, these findings may have been limited by a short study window L Carnitine Benefits: A Complete Research Based Guide Didn't another study show carnitine was good for the heart? Risks and benefits of carnitine supplementation in diabetes. Semantic Scholar Supplements and chronic pain: What does the research say? Some studies suggest possible benefits for: Acetyl L Carnitine (energy for cells; studied in diabetic nerve pain) Alpha Lipoic Acid (antioxidant; may ease nerve pain,