Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Cell Death & Disease For CKD, Id separate the proven support from the experimental but interesting category., Astragalus root extract is probably the most tried and true natural compound Id look at first. Theres Glutathione deficiency alters the vitamin D metabolizing enzymes CYP27B1 and CYP24A1 in human renal proximal tubule epithelial cells and kidney of HFD fed mice ScienceDirect The Vicious Consequences of Chronic Kidney Disease on Cognitive Impairment and Alzheimer's Disease ACS Chemical Neuroscience N acetylcysteine in Kidney Disease: Molecular Mechanisms, Pharmacokinetics, and Clinical Effectiveness ScienceDirect How Common is Kidney Disease in Diabetes? Providence Specialty Centre